10 million+
datapoints
Your biochemistry is unique! We measure over 10 million data points from expressed genes per sample from microbial (oral and gut) and human cells, allowing us to quantify, influence, and monitor your cellular and microbial pathways. This lets us know the nutrients or ingredients you need in order to stimulate or suppress certain functions and bring you back into balance.
We focus on key areas that have an impact on overall health
Insights available with Full Body Intelligence
![[Icon] Biological Age](png/frame_257.png)
Biological Age
We assess the activities of your gut microbiome, your cells, and your oral microbiome to determine how well you are aging at a cellular level compared with other people your age.
Your nutrition recommendations are designed to help you optimize specific biological functions responsible for how you’re aging internally.
![[Icon] Gut Health](png/frame_257__2_.png)
Gut Health
Your gut microbiome is home to trillions of microbes that have a direct influence on everything from your mood to how you digest foods and even how your immune system responds to infections or allergens.
Your nutrition recommendations are designed to optimize your digestion, strengthen gut lining, and boost richness & microbiome diversity.
What we report on:
Nutrient absorption
Beneficial & harmful microbial activities
Intestinal barrier health
Signatures of inflammation in the gut
![[Icon] Oral Health](png/frame_256__2_.png)
Oral Health
Oral health impacts systems beyond the mouth and is intricately connected to your cardiovascular, immune, bone, and brain health.
Your nutrition recommendations are designed to rebalance your oral microbiome and lower the risk of cavities, bad breath, and leaky gums.
What we report on:
Activities of microbes in the mouth that contribute to gum inflammation
Activities of microbial pathways that cause bad breath
Microbial activities that lead to cavities and tooth decay
![[Icon] Cellular & Energy Efficiency](png/frame_256__4_.png)
Cellular & Energy Efficiency
When cells lack the nutrition they need, they can't keep up with the metabolic demands of the body, which leads to a loss of function and is the earliest measurable indicator of aging and health decline.
Your nutrition recommendations are designed to kickstart your cellular repair and cellular support processes.
What we report on:
Aging of your cells
Cellular stress
Cellular inflammation
Mitochondrial health
![[Icon] Inflammation Response](png/frame_256__3_.png)
Inflammation Response
Prolonged inflammation due to factors such as poor diet, increased stress, and environmental toxins promote health decline.
Your nutrition recommendations are designed to support your body’s response to stress and immune tolerance.
What we report on:
Overall balance of your body’s pro- & anti-inflammatory activity
Immune system’s ability to address inflammation
Cellular functions under stress
Microbial stress
![[Icon] Brain & Cognitive Health](png/frame_256__1_.png)
Brain & Cognitive Health
The gut microbiome aids in the development of our brain and nervous system as well as the management of neurological functions.
Your nutrition recommendations are designed to boost brain health and functions that support your cognitive and mood health.
What we report on:
Serotonin production assisting pathways
Microbial activities which contribute to the production of GABA
Activities that might negatively impact focus
Activities that impact your body’s pH balance
![[Icon] Immune System Health](png/frame_257__1_.png)
Immune System Health
A healthy immune system is essential for fighting off outside invaders like viruses, bacteria, and fungi, neutralizing environmental toxins, and preventing changes within cells that lead to a decline in biological functions.
Your nutrition recommendations are designed to help support your body’s alarm system and repair mechanism.
What we report on:
Overall immunity
Body’s preparedness to fight off bad viruses & bacteria
Body’s ability to clear toxins
Manage oxidative stress
![[Icon] Heart & Cardiometabolic Health](png/frame_256.png)
Heart & Metabolic Health
While many people simply think of managing their cholesterol to improve their cardiovascular health, in reality, many factors are at play, including oxidative stress, endothelial function, kidney function, and vitamin and mineral status.
Your nutrition recommendations are designed to optimize functions related to your heart health.
What we report on:
Indicators of high oxidative stress
Activities that promote inflammation
Vascular health
Cholesterol metabolism
All Full Body Intelligence™ Scores
Where we look for underlying signals
![[Scores & Recs] Underlying Signals | Top - Icons - Gut Microbiome](http://images.ctfassets.net/qk4l4jfatr3e/2aa0lQE1xTO1iBTxtdsdss/80ec5e2e0551b2408c795c87b889a34b/gut-icon.svg){kind=icon}
Gut
Microbiome
+
![[Scores & Recs] Underlying Signals | Top - Icons - Oral Microbiome](http://images.ctfassets.net/qk4l4jfatr3e/5FTvhE5cAattR2hmp8WbKg/cfbcb4ace4f7664e286f80131a110e2c/oral-icon.svg){kind=icon}
Oral
Microbiome
+
![[Common Icon] Cell](http://images.ctfassets.net/qk4l4jfatr3e/7itiu6ioeaHGzdVL9c2gqe/0ecdb0801f5d145b270cd089f39d6509/cellular-icon.svg){kind=icon}
Cellular
Function
Gut Microbiome
As the largest micro-ecosystem in the human body, your gut microbiome is in a symbiotic relationship with you as its “host". A great deal of research has produced evidence that metabolites produced in your gut microbiome play a key role in maintaining balance and overall health for your entire body.
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Science also shows that they influence the development of many diseases, including neurodegenerative diseases, cardiovascular diseases, metabolic diseases, and gastrointestinal diseases.
Our approach is to analyze what’s being produced in your gut microbiome that may impact your health and offer a personalized, food and nutrient-specific plan to bring your back into balance.
Are there bad microbes?
Harmful microorganisms are called pathogens and can cause infection or disrupt normal patterns in health. However, harmful pathogens only make up a tiny fraction of the microbes that live inside us. Other than that, many commensal microbes within our body can act in beneficial or harmful ways depending on their environment (health, stress level, and access to different nutrients). This is why we rather classify microbial activities as either harmful or beneficial rather than specific microbes themselves. Like humans, whether you are bad depends on your actions, which can be influenced by the environment you live in.
What are the signs of microbial imbalance?
Signs can vary significantly from person to person, which is why Viome prioritizes testing before recommending a plan of action. However, certain signs are considered hallmarks of gut microbial imbalance, such as digestive discomfort, occasional gas and bloating, brain fog, fatigue, difficulty concentrating, excessive food cravings, an overactive (or underactive) immune response, depression, difficulty falling asleep, and many others. This is why we recommend testing.
Oral Microbiome
The oral microbiome, the second largest micro-ecosystem in your body, has been the focus of intense research in recent years. As the entry point to your entire body, it is no surprise that in addition to mouth diseases, the oral microbiome has been implicated in several systemic diseases.
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Problems with oral health caused by underlying, suboptimal microbial activities—such as cavities, gum disease, and tooth loss—can and do affect overall health. Science has linked the oral microbiome to many chronic diseases and health issues, including cognitive impairment, mental health, diabetes, sleep, pregnancy outcomes, many types of cancers, neurological disorders, rheumatoid arthritis, cardiovascular diseases, and cystic fibrosis.
How does food impact the oral microbiome?
Our food helps fuel our body, but it also is broken down into many compounds that help to support the microorganisms inside our body. In the mouth, as we chew, food particles are also used as fuel for various oral bacteria. In addition, the acidity level of our food can significantly sway the balance of harmful microorganisms. If we aren’t consuming enough fibrous and alkaline foods, our diet can impact the balance of organisms in the mouth and lead to changes in our dental health, gum health, and even interfere with other regions of the body
What can impact the health and balance of the oral microbiome?
A number of factors can contribute to health and balance, and conversely an imbalance of our oral microbiome. Our diet, lifestyle, dental hygiene, smoking and alcohol habits, as well as our family members and partners all contribute to the microorganisms in our mouth.
What are signs of an unhealthy oral microbiome?
Typical signs associated with an unhealthy oral microbiome may include ‘biofilm’ formation on the teeth. Also known as plaque, biofilm acts as a cityscape for colonizing bacteria. Excessive plaque formation can contribute to an accumulation of pathogens and toxic byproducts that can cause inflammation in and around the gums. This may appear as bleeding or easily damaged gums from brushing or flossing. Discomfort, excessive bleeding, and even sores inside the mouth may all be pointing toward issues of an imbalance in the oral microbiome.
Cellular Function
The human body is composed of trillions of cells that provide structure for the body, converting nutrients into energy and carrying out specialized functions. Inflammation from the activities of your gut microbiome and oral microbiome can be problematic for your cells.
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When your cells are functioning optimally, they produce enough energy to sustain your needs and are efficiently “cleaning up” cellular waste, like free radicals. When cells lack the nutrition they need, they can't keep up with the metabolic demands of the body, which leads to a loss of function and is the earliest measurable indicator of aging and declining health.
The food and nutrients you put into your body can affect the cells’ ability to replicate properly and to make the bodily tissues you need to repair daily damage, build new muscle, and reduce the effects of aging.
What are the hallmarks of cellular aging?
Our cells are very high-functioning machines, capable of healing and repairing old parts. This occurs naturally throughout the lifespan of a cell as performing its function sometimes results in damage. For example, organelles like the mitochondria create energy in the form of ATP from our food. As a byproduct, harmful free radicals occur causing oxidative damage. However, our cells naturally produce glutathione, the master antioxidant, that is particularly effective at neutralizing these free radicals. Cellular aging occurs when too much oxidative stress is created and our cells aren’t capable of neutralizing their effects. Consequently, our mitochondria become damaged and make it more difficult to generate energy. Over time, this can affect the overall health of a cell, and make it more difficult to repair. In addition, chronic oxidative stress can begin to harm other parts of the cell, such as our DNA. When our genetic code is broken down, a cell can no longer repair itself or replicate. As this occurs to many different cells, our body slowly loses the capacity to create new, youthful cells to replace the old ones, resulting in cellular and bodily aging.
What are microbial cells?
Also known as microorganisms, microbial cells can account for a variety of types of microscopic living organisms, including bacteria, archaea, prokaryotes, fungi, and even viruses.
What does Viome report about my cellular function?
Using a sample of your blood, we are able to assess what microbial byproducts and their effects are on our human cells. This gives us a clear picture of your circulating inflammation, the health of your mitochondria (the powerhouses of the cell), indications of oxidative stress levels, and even how combined they play a part in your biological aging. We can also see a number of other factors that contribute to your overall health landscape, such as how your diet is either aiding or harming your ability to heal and regenerate. In some cases, we can even see certain dietary deficiencies, such as your vitamin D status or whether you may benefit from an increase in fiber to help boost the health of your intestinal lining.
Mapping your scores to personalized nutrients
Lower the risk of a leaky gut
A leaky gut occurs when your intestinal lining doesn’t have “healthy boundaries”, with gaps allowing certain microbes and particles to slip from your digestive tract into bloodstream.
Learn more
This starts a chain reaction from the gut barrier breaking down to causing low-grade chronic inflammation; if untreated, it can lead to various health conditions.
Promote healthy blood pressure
The kidneys impact heart health through their central role in the regulation of blood pressure as well as their ability to filter blood to remove metabolites that can injure your blood vessels and other tissues.
Learn more
Recently, studies looking at the oral microbiome have found they also can impact our mood and brain function through various activities that influence cognition. Not only are we able to monitor how much of these neurotransmitters are produced, but we’re also able to recommend foods that help support balance in your microbiome with effects that can trickle down to even your mood.
Help relieve gas and bloating
Cruciferous vegetables like cauliflower or broccoli contain nutrients like vitamins, minerals, and antioxidants like glucosinolates. Although these antioxidants can be potent warriors against illness, many people feel uncomfortable and bloated after consuming vegetables rich in glucosinolates.
Learn more
If your Viome test shows highly active pathways that result in sulfide gas, glucosinolates may not be good for you because they can be turned into more sulfide gas by your gut microbiome. In such cases, foods like broccoli - rich with glucosinolates - may do more harm than good. We've analyzed tens of thousands of people and learned that 30% of our users have high pathway activity for microbial sulfide gas production.
Promote emotional balance and a better mood
Many of our neurotransmitters -or the hormones that control our brain’s activity and our mood- are created inside the gut with the help of microorganisms that live there.
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Recently, studies looking at the oral microbiome have found they also can impact our mood and brain function through various activities that influence cognition. Not only are we able to monitor how much of these neurotransmitters are produced, but we’re also able to recommend foods that help support balance in your microbiome with effects that can trickle down to even your mood.
Promote a resilient immune system
No one wants an underactive immune response when trouble starts, but you certainly don’t want an over-active one either! In your results, you’ll find scores that break down the level of inflammation inside you, as well as how active your immune system is.
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To keep your immune system right where it belongs requires keeping it right in the middle of activity. Learning where your immune system falls on this scale can help us determine whether issues in your body stem from too little or too much immune system activation.
Help your body cope with stress
There are a lot of factors that can cause your cells to get stressed out, but your test samples provide a lot of information about contributing causes. We can see all sorts of information, including the levels of oxidative stress in your cells.
Learn more
We can also see how your gut microbiome may produce toxic or inflammatory stress-inducing byproducts (e.g., putrescine, ammonia, cadaverine). In addition, if you consume a high salt diet - some signs may suggest ‘salt stress’ signaling. We don’t just see how stressed out your cells are, we can pinpoint what key factors might be causing it.
No universal healthy food or supplement
Food and supplements help your body function and repair itself, but no two people react to all food and supplements the same way. Here are a few ways in which food and supplements that are generally considered “healthy” might turn out to be on your Avoid list right now.
1 High Uric Acid
2 High Bile Acid
3 High TMA
4 High Sulfide Gas
Goal of your recommendations
Prevent an increase in circulating uric acid levels, which promotes gouty arthritis, kidney stones, and hypertension.
Avoid these foods
Avoid these supplements
Turning your samples into Health Scores
The insights and innovation behind your unique supplement formula are made possible by our team of researchers, clinical nutritionists, and scientists from all over the world who contribute our platform.
Test + Supplement Bundles
Most Comprehensive
Our most comprehensive nutrition health plan for full body resilience & longevity.
Full Body Health Solutions
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Our most comprehensive nutrition health plan for full body resilience & longevity.
Nourish your gut microbiome with personalized probiotics + prebiotics & supplements for a healthier gut.
Gut Health Solutions
From
Nourish your gut microbiome with personalized probiotics + prebiotics & supplements for a healthier gut.
Powered by world class scientists
Viome's nutrition recommendations and your unique supplement formula are driven by proprietary RNA sequencing technology and extensive scientific research from top institutes.
A few of our Data Science & Systems Biology Experts
Eric
Principal Scientist in
Computational Systems Biology
Eric is a life scientist dedicated to transforming health for personal empowerment. At Viome, he is a computational principal scientist and leads the Systems Biology team through the process of designing wellness scores for Viome users and research efforts for Viome Life Sciences.
Grant
Translational Science
Clinical Expert
Dr. Grant Antoine is a naturopathic doctor passionate about patient empowerment and education. At Viome, Dr. Antoine is involved in clinical trial design and developing nutritional and supplement interventions for Viome’s user recommendations and efficacy studies.
Lan
Data Science &
Bioinformatics
Lan trained as a computational biologist, has a deep and broad understanding in biological data and its clinical applications. At Viome, Dr. Hu leads the team of Data Science and Bioinformatics to make sense of the vast amount of metatranscriptome NGS data from microbiome and human, to support the wellness as well as diagnostics products.
“Welcome to the most promising
new frontier in medicine.”
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